ObjectiveFrontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two distinct degenerative disorders with overlapping genetics, clinical manifestations, and pathology, including the presence of TDP-43 aggregates in nearly 50% of patients with FTD and 98% of all patients with ALS.Here, we evaluate whether different genetically pred

Tumor necrosis factor-alpha antagonism is an important treatment strategy in patients with rheumatoid arthritis, psoriatic arthritis, vasculitis, and ankylosing spondylitis.Adalimumab is one of the well-known tumor necrosis factor-alpha blocking agents.There are several side effects reported in patients with adalimumab therapy.Cardiac side effects

Orchids are among the most threatened plants due to habitat loss and illegal harvesting for horticultural demands.Sabah is a centre of orchid diversity, with approximately 1300 species of which 250 orchid taxa are endemic to Sabah.In this study, we conducted an BLACK RICE RAMEN IUCN Red List assessment on 136 endemic species and used Maximum Entrop

Ming-Chen Sun,1,* Xiao-Ling Xu,1,* Xue-Fang Lou,2 Yong-Zhong Du1 1Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, People’s Republic of BLACK RICE RAMEN China; 2School of Medicine, Zhejiang University City College, Hangzhou 310015, People’s Republic of China*These authors contributed